Most patches handle regular washing fine, but turning the garment inside out before a wash cycle protects the stitching and color.
Iron-on patches should be re-pressed if an edge starts to lift — a few seconds of heat with a cloth barrier usually reseats the adhesive.
Leather patches age best with the occasional wipe-down and by keeping them out of prolonged direct sun, which can dry and crack the surface over time.
Velcro-backed patches last longest when the hook side is kept free of lint and thread buildup, which otherwise weakens the hold.